The effects of whole cereal meals on growth, nutrient digestibility, glycaemic response and gut morphologywerestudied in gilthead seabream juveniles. Groups of 30 fishes (in triplicate) were fed four isoproteic (47%) andisolipidic (16%) diets including 30% of wheat, corn, barley or rye meals. Growth performance was higher in fishfed the wheat diet than the rye diet. Feed efficiency and protein efficiency ratio were higher with the wheatand barley diets than in the other groups. There were no differences in apparent digestibility coefficients(ADCs) of dry matter, protein or lipids among diets. However, ADC of corn and barley starch was lower thanthat of wheat and rye starch. Average plasma glucose levelswere lower in fish fed the barley diet. Plasma glucosepeaked 10 h after feeding in all groups except the corn group which peaked 8 h after feeding. Shorterhyperglycaemia duration was observed in fish fed the corn diet (12 h) than the other diets (N12 h). Gutmorphologywas similar in all groups irrespective of the sampling point. Based on growth performance, feed utilizationefficiency, ADC of starch and glycaemic response we can conclude that wheat and barley are more efficientlyused than corn or rye by gilthead seabream juveniles and thus are the preferential cereal sources to be used asplant feedstuffs in diets for this species.